W. GOTTSCHALK und Vera MILUTINOVIĆ
UNTERSUCHUNGEN ZUR HETEROSIS BEI SELBSTBEFRUCHTERN. II. DIE SAMENPRODUKTION UND ANDERE LEISTUNGSMERKMALE VON BASTARDEN VERSCHIEDENER PISUM-MUTANTEN IM VERGLEICH ZU DEN ELTERLICHEN GENOTYPEN [Abstract]
Milanka JANKOVIĆ, Ž. JESTROVIĆ, Lj. ZEČEVIĆ i M. KUBUROVIĆ
GENETICAL AND CYTOGENETICAL STUDY OF HYBRIDS BETWEEN TETRAPLOID AND HEXAPLOID SPECIES OF WHEAT [Abstract]
A. TUCOVIĆ and M. JOVANOVIĆ
IRREGULAR SEXUAL REPRODUCTION OF THE PUBESCENT BIRCH (BETULA PUBESCENS EHRH.) AFTER FERTILIZATION BY THE YELLOW BIRCH (BETULA ALLEGHANIENSIS BRITT.) [Abstract]
N. COMAN and B. WALLACE
INBREEDING DEPRESSION AND ENVIRONMENTAL STRESS [Abstract]
M. DENIĆ, Kosana KONSTANTINOV and J. DUMANOVIĆ
RELATIONSHIP BETWEEN RIBONUCLEASE ACTIVITY AND CONTENT OF BASIC AMINO ACIDS IN MAIZE ENDOSPERM [Abstract]
Marija VRDOLJAK and C. HERMAN
MUTANTS OF ASPERGILLUS NIDULANS WITH A BROWN MYCELIUM [Abstract]
P. KALIČANIN, Jovanka NIKOLIŠ and Živana LAĆA
CLINICAL AND CYTOGENETIC ANALYSIS OF A »CRI DU CHAT« SYNDROME [Abstract]
Ž. GAVRILOVIĆ
ON PAPILLARY RIDGES IN A POPULATION FROM NOVI SAD [Abstract]
Verica BOŽIĆ and Ž. GAVRILOVIĆ
AN INVESTIGATION OF TASTE SENSITIVITY TO PTC IN A POPULATION FROM SREMSKA MITROVICA WITH SPECIAL EMPHASIS UPON THE INFLUENCE OF SMOKING [Abstract]
P. DROBNJAK, I. DAMJANOV and Ljiljana ZERGOLLERN
46, XY WOMEN AND GONADAL TUMOURS [Abstract]
A. KURJAK, Usama ABDULLA, Mary LUCAS and D. TALBERT
ULTRASOUND DIAGNOSIS IN PREGNANCY AND EFFECT ON MATERNAL AND FETAL CHROMOSOMES [Abstract]
I. LIGUTIĆ and Z. SINGER
A CONTRIBUTION TO THE INTERPRETATION OF THE XYY SYNDROME [Abstract]
D. EFINSKI, B. APOSTOLOVSKI, B. RISTEVSKI. S. DARKOVSKI and D. POPOVSKI
DEVIATIONS OF BEHAVIOUR AMONG MALES WITH NUMERICAL X-CHROMOSOME ABERRATIONS [Abstract]
Ljiljana ZERGOLLERN i Vlasta HITREC
ENIGMAS OF CHROMOSOMAL ABNORMALITIES SOLVED BY G-BANDING METHOD [Abstract]
Angelina PETROVIĆ i Branislava AJDARIĆ
COMPARATIVE CITOGENETICAL ANALYSIS OF DOWN'S SYNDROME USING AN AUTORADIOGRAPHIC METHOD AND A BANDING TECHNIQUE [Abstract]
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 117-134
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
UNTERSUCHUNGEN ZUR HETEROSIS BEI SELBSTBEFRUCHTERN. II. DIE SAMENPRODUKTION UND ANDERE LEISTUNGSMERKMALE VON BASTARDEN VERSCHIEDENER PISUM-MUTANTEN IM VERGLEICH ZU DEN ELTERLICHEN GENOTYPEN
W. GOTTSCHALK und Vera MILUTINOVIĆ
Institut für Genetik der Universitat Bonn, BRD
Abstract
Gottschalk, W. und Milutinovic, V. (1973): Untersuchungen zur Heterosis bei Selbstbefruchtern. II. Die Samenproduktion und andere Leistungsmerkmale van Bastarden verschiedener Pisum-Mutanten im Vergleich zu den elterlichen Genotypen. - Genetika, Vol. 5, No. 2, 117-134.
Die rontgeninduzierte Erbsen-Mutante 489C ist mit der Nor-malform und 15 anderen Mutanten gekreuzt worden. Alle Bastar de zeigen einen hohen Grad. von Heterosis, der sich im Hinblick auf die Kriterien »Samenzahl je Hülse«, »Hülsenzahl je Pflanze« und »Samengewicht« äußert. In Abhängigkeit vom zweiten Kreuzungspartner werden von den Bastarden Samenmengen von 200-500% der Vergleichswerte der Ausgangsform produziert. Diese Ergebnisse wurden übereinstimmend in drei aufeinander-folgenden F1-Generationen erhalten. Kreuzungen. an denen die verbänderte Mutante nicht beteiligt war, führten nicht zur Heterosis.
Die genetische Konstitution der verbänderten Mutante ist äußerst kompliziert; während der Bestrahlung des betreffenden Embryos sind mindestens 10 Gene mutiert. Sie sind durch Kreuzungen mit anderen Mutanten unseres Sortiments in vielfältiger Weise kombiniert worden; dadurch ist eine große Anzahl verschiedener homozygoter Rekombinationslinien entwickelt worden. Sie werden für die Klärung der genetischen Grundlagen der Verbänderung der Mutante 489C sowie der vorliegenden hete-rotischen Erscheinungen verwendet.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 135-147
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
GENETICAL AND CYTOGENETICAL STUDY OF HYBRIDS BETWEEN TETRAPLOID AND HEXAPLOID SPECIES OF WHEAT
Milanka JANKOVIĆ, Ž. JESTROVIĆ, Lj. ZEČEVIĆ i M. KUBUROVIĆ
Institut za strna žita, Kragujevac
and
Institut za biološka istraživanja, Beograd, Jugoslavija
Abstract
Janković. M., Jestrović, Ž., Zečević, Li. and Kuburović, M. (1973): Genetical and cytogenetical study of hybrids between tetraploid and hexaploid species of wheat. - Genetika, Vol. 5, No. 2, 135-147.
In Yugoslavia there is much interest in a rapid improvement in the yield of durum wheat, which is important in the production of pastes. With this in mind, crosses between hexaploid and tetraploid wheats have been made.
Hybrid plants in the F4 and F2 generations have large spikes with many spikelets and florets which basically contribute to an increased yield in grain crops. However, there also exists a partial sterility caused by cytological abnormalities. In F3 generation cytological stability and increased fertility were observed. Analysis of the behaviour of F1 - F3 generations at meiosis is presented and discussed.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 149-156
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
IRREGULAR SEXUAL REPRODUCTION OF THE PUBESCENT BIRCH (BETULA PUBESCENS EHRH.) AFTER FERTILIZATION BY THE YELLOW BIRCH (BETULA ALLEGHANIENSIS BRITT.)
A. TUCOVIĆ and M. JOVANOVIĆ
Forestry Faculty and Institute for Forestry and Wood Industry Belgrade, Yugoslavia
Abstract
Tucović, A. and Jovanović, M.: Irregular sexual reproduction of the pubescent birch (Betula pubescens Ehrh.) after fertilization by the yellow birch (Betula alleghaniensis Britt.). Genetika Vol. 5, No. 2, 149-156.
In this paper is described the phenomenon of segregation of parent phenotypes in the F1 generation, after fertilizing a number of pubescent birch trees with the pollen of one yellow birch tree.
The appearance of plants with the maternal phenotype in the F1 generation points to the existence of partial diploid apomixis (pseudogamy) in the analysed pubescent birch trees.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 157-166
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
INBREEDING DEPRESSION AND ENVIRONMENTAL STRESS
N. COMAN and B. WALLACE
Cornell University, Ithaca, New York, U.S.A.
Abstract
Coman, N. and Wallace, B. (1973): Inbreeding depression and environmental stress. - Genetika, Vol. 5, No. 2, 157-166.
Inbreeding depression, measured as the relative decrease in the number of adult progeny produced by D. melanogaster flies subjected to successive generations of brother-sister ma-tings, has been shown to vary with environmental stress. Stress for the inbred larvae was provided by the presence of sepia larvae. The greater the number of sepia parents (2, 3, 4, and 6 females), the greater the observed rate of inbreeding depression during the first five generations of inbreeding. Starting about the 6th generation of inbreeding and continuing rather consistently until the end of the experiment (generation 11), the relative number of wild type progeny tended to increase. An increase of this sort had been predicted earlier provided that the measure of inbreeding depression relied on competition between the inbred individuals themselves; nevertheless, it is not clear that the observed increase supports the argument upon which this prediction was based.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 167-172
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
RELATIONSHIP BETWEEN RIBONUCLEASE ACTIVITY AND CONTENT OF BASIC AMINO ACIDS IN MAIZE ENDOSPERM
M. DENIĆ, Kosana KONSTANTINOV and J. DUMANOVIĆ
INEP, 11080 Zemun, Yugoslavia
Abstract
Denić, M., Konstantinov, K. and Dumanović, J. (1973): Relationship between ribonuclease activity and content of basic amino acids in maize endosperm. - Genetika, Vol. 5, No. 2, 167-172.
The influence of the opaque-2 gene on the relationship between ribonuclease activity and content of basic amino acids in maize endosperm was studied. Analyses of material from different genetic backgrounds showed that in all cases the increased amounts of basic amino acids in opaque-2 endosperm were accompanied by increased ribonuclease activity. The use of the higher ribonuclease activity in the mutant as marker for the opaque-2 gene when the presence of the gene cannot be visually recognized is discussed.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 173-177
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
MUTANTS OF ASPERGILLUS NIDULANS WITH A BROWN MYCELIUM
Marija VRDOLJAK and C. HERMAN
Biological Institute, University of Zagreb, 41000 Zagreb, Yugoslavia
Abstract
Vrdoljak, M., Herman, C. (1973): Mutants of Aspergillus nidulans with a brown mycelium. - Genetika, Vol. 5, No. 2, 173-177.
The aim of the work was to find the cause of the brown mycelium of several mutant strains of Aspergillus nidulans. Balanced heterokaryons and diploids were synthetized between mutants and strains with a normal mycelium from Glasgow. These strains were then crossed with strains with known markers, and a few looi for the brown colour of the mycelium were determined in their linkage groups.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 179-184
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
CLINICAL AND CYTOGENETIC ANALYSIS OF A »CRI DU CHAT« SYNDROME
P. KALIČANIN, Jovanka NIKOLIŠ and Živana LAĆA
Laboratorija za humanu citogenetiku Zavoda za mentalno zdravlje, Beograd, Jugoslavija
Abstract
Kaličanin. P., Nikoliš, J. and Laća, 2. (1973): Clinical and cytogenetic analysis of a »Cri du chat« syndrome. - Genetika, Vol. 5, No. 2, 179-184.
As discribed by Lejeune et al. (1963), deletion of the short arm of chromosome seems to be the most frequent deletion occurring with autosomes. According to Polani (1969) and Berger (1972) more than a hundred of cases with such a syndrome have been described up to now.
This paper reports a case of a »Cri du chat« syndrome discovered during a clinical check in a Home for the Mentaly Retarded and confirmed by cytogenetic analysis.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 185-188
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
ON PAPILLARY RIDGES IN A POPULATION FROM NOVI SAD
Ž. GAVRILOVIĆ
Zavod za biologiju, Medicinski fakultet, Novi Sad, Jugoslavija
Abstract
Gavrilović, Ž. (1973): On papillary ridges in a population from Novi Sad. - Genetika, Vol. 5, No. 2, 185-188.
The author examined dermopapillary ridges in 200 male and 200 female Serbs from Novi Sad. The mean values for the total ridge count are 141,75 in men and 124,45 in women. These figures for Serbs are compared with those from other populations.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 189-196
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
AN INVESTIGATION OF TASTE SENSITIVITY TO PTC IN A POPULATION FROM SREMSKA MITROVICA WITH SPECIAL EMPHASIS UPON THE INFLUENCE OF SMOKING
Verica BOŽIĆ and Ž. GAVRILOVIĆ
Zavod za biologiju Medicinskog fakulteta, Novi Sad, Jugoslavia
Abstract
Bozić, V. and Gavrilović, Ž. (1973): An investigation of taste sensitivity to PTC in a population from Sremska Mitrovica with special emphasis upon the influence of smoking. - Genetika, Vol. 5, No. 2, 189-196.
The authors examined taste sensitivity to phenylthiocarbamide (PTC) in a population from Sremska Mitrovica with special emphasis the effect of smoking. Six hundred persons of both sexes ranging from 16 to 68 years of age were examined. The frequency of non-tasters was 26.33%. There exist no differences in mean values of PTC taste thresholds between smoker and non-smoker in relation to sex.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 197-208
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
46, XY WOMEN AND GONADAL TUMOURS
P. DROBNJAK, I. DAMJANOV and Ljiljana ZERGOLLERN
Klinika za ženske bolesti i porode, Klinika za dječje bolesti Rebro i Zavod za patologiju Medicinskog fakulteta Sveučilišta u Zagrebu, Zagreb, Jugoslavija
Abstract
Drobnjak, P., Damjanov, I. and Zergoilern, Lj. (1973): 46 XY women and gonadal tumors. - Genetika, Vol. 5, No. 2, 197-208.
Patients with the complete female phenotype and with feminine external genitals, in spite of their 46, XY karyotype and male gonosomal pair, can be divided into the following clinical syndromes: complete testicular feminization, syndrome of rudimentary testes and pure gonadal dysgenesis. Patients with two gonads completely destroyed by tumours represent a separate group, because they cannot be classified in the above mentioned groups with certainty.
Histological analysis of the patients with gonadal tumours is different according to the degree of gonadal - testicular differentiation. Examining the gonadal neoplasms in three patients with testicular feminization we observed only hyperplasia, i.e testicular adenoma of Leydig or Sertoli cells.
Among the four patients with pure gonadal disgenesis, one had a gonadoblastoma and two patients had both gonads replaced by tumorous tissue (disgerminoma and gonadoblastoma). It seems that the risk of malignant tumours in 46. XY women becomes greater as the degree of gonadal differentiation is poorer.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 209-226
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
ULTRASOUND DIAGNOSIS IN PREGNANCY AND EFFECT ON MATERNAL AND FETAL CHROMOSOMES
A. KURJAK, Usama ABDULLA, Mary LUCAS and D. TALBERT
Klinika za ženske bolesti i porode Medicinskog fakulteta Sveučilišta u Zagrebu, Zagreb, Jugoslavija,
Institut za ginekologiju i opštetriciju Sveučilišta u Londonu and
Galton laboratorija,University College, London
Abstract
Kurjak, A., Abdulla, U.. Lucas, M. and Talbert, D. (1973): Ultrasound diagnosis in pregnancy and effect on maternal and fetal chromosomes. - Genetika, Vol. 5, No. 2, 209-226.
Some recent reports have suggested that ultrasonic radiation, as used in clinical obstetrics, might cause genetic damage to the developing fetus. In this study the effect of diagnostic pulsed and continuous - wave ultrasound on maternal and fetal chromosomes was studied in patients admitted for hysterotomy. In vitro experiments have been undertaken to assess the effect of ultrasound on chromosomes of human lymphocyte culture. No difference could be detected between the numbers of cells with aberration in the insonated and control cultures.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 227-235
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
A CONTRIBUTION TO THE INTERPRETATION OF THE XYY SYNDROME
I. LIGUTIĆ and Z. SINGER
Institut za zaštitu majki i djece, Zagreb i Opća bolnica »Dr O. Novosel«, Zagreb, Jugoslavija
Abstract
Ligutić, I., Singer, Z. (1973): A contribution to the interpretation of the XYY syndrome. - Genetika, Vol. 5, No. 2, 227-235.
The typical phenotype of the XYY aberration has not yet been established. A tall stature is the most constant sign of this gonosomic anomaly. In a number of XYY persons this aberration favours the development of an immature personality with less stable behavioural control which together with unfavourable environmental factors may lead to delinquency.
It is necessary to make efforts to prevent the development of antisocial behaviour by early detection and suitable care of the child. The significance of the XYY anomaly as a criminogenic factor will be established by further cytogenetic and psychiatric studies on unselected adult males and with long-term follow up studies of the psychosomatic development of XYY males discovered as newborn infants.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 237-244
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
DEVIATIONS OF BEHAVIOUR AMONG MALES WITH NUMERICAL X-CHROMOSOME ABERRATIONS
D. EFINSKI, B. APOSTOLOVSKI, B. RISTEVSKI. S. DARKOVSKI and D. POPOVSKI
Zavod za rehabilitaciju dece i omladine - Laboratprija za humanu citogenetiku, 91000 Skopje, Jugoslavija
Abstract
Efinski, D., Apostolovski, B., Ristevski, B., Darkovski, S., Popovski, D. (1973): Deviations of behaviour among males with numerical X - chromosome aberrations. - Genetdka, Vol. 5, No. 2, 237-244.
Since males with a supernumerary X chromosome are more liable than others to mental subnormality. mental disease, epilepsy and antisocial conduct, this cytological research was undertaken: (1) in a group of males with mental subnormality and deviant behaviour, (2) in a group of mentally subnormal males with common behaviour, (3) within a group of mentally subnormal males with epilepsy, and (4) a group of delinquent children without mental subnormality and epilepsy.
Clinical, psychological and psychiatrical methods have been applied in this investigation. The method of Moorhead et al. (1960) was used for chromosome analysis, but for determination of sex-chromatin, staining with leucobasic fuchsin was found to be more satisfactory.
The case material comprised 3 subjects with chromosome aberrations: one patient with 47 XXY, another one with double aneuploidy presented by 48,XXY,G-t, and a case characterized by mosaicism with a 47,XXY/46,XY chromosome constitution. All cases where the supernumerary X chromosome was found, belonged to the group of males with mental subnormality, deviant behaviour and phenotype characteristics which entirely co-responded to the genotype constitution.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 245-252
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
ENIGMAS OF CHROMOSOMAL ABNORMALITIES SOLVED BY G-BANDING METHOD
Ljiljana ZERGOLLERN i Vlasta HITREC
Citogenetski laboratorij Klinike za Dječje bolesti - Rebro. 41000 Zagreb, Jugoslavija
Abstract
Zergollern. Lj. and Hitrec, V. (1973): Enigmas of chromosomal abnormalities solved by G-banding method. - Genetika. Vol. 5, No. 2, 245-252.
A brief
introduction to the historical development of identification of human
chromosomes was followed by a survey of these methods. The first results
obtained by a modification of the denaturation-renaturation technique according
to S u m n e r (1971) are presented by the authors. This method was valuable
particularly for the identification of chromosomes in translocation or
for some other structural chromosomal abnormalities, especially the
Robertsonian-type of translocation. It would not have been possible to identify
these chromosomal aberrations by the usual Moorhead technique. The somewhat
modified Sumner's method applied here can be used in any laboratory, as it is
simple and reliable, and requires no expensive laboratory equipment.
Published in „GENETIKA“ Vol. 5, No.2 (1973), pp. 253-261
© 1973 Serbian Genetics Society
S. Bajića 1, 11185 Belgrade-Zemun
Serbia
Original scientific paper
COMPARATIVE CITOGENETICAL ANALYSIS OF DOWN'S SYNDROME USING AN AUTORADIOGRAPHIC METHOD AND A BANDING TECHNIQUE
Angelina PETROVIĆ i Branislava AJDARIĆ
Laboratorija za humanu citogenetiku, Institut za biološka istraživanja, Beograd, Dečija klinika Medicinskog fakulteta, Beograd, Jugoslavija
Abstract
Petrpvic, A. and Ajdaric, B. (1973): Comparative citogeneti-cal analysis of Down's syndrome using an autoradiographic method and a banding technique. - Genetika, Vol. 5, No. 2, 253-261.
In previous works the cause of Down's syndrome was explained as a chromosomal aberration of the human karyotype namely trisomy in the group 21-22. The autoradiographic method was rarely used to help in the identification of the trisomic pair in the 21-22 group.
In this work, a cytogenetical analysis of two patients with Down's syndrome was done, using comparatively autoradiographic and banding techniques.
Autoradiographic anlysis showed, that three chromosomes are late replicators. At the same time, the banding technique revealed the same pattern (heterohromatic region) on three chromosomes. In the second pair, dark coloured (heterohromatic regions) were always present in the centromeric regions, and this pair of chromosomes is the early replicator of the group 21-22.